(R)-(-)-JQ1 Enantiomer

CAS No. 1268524-71-5

(R)-(-)-JQ1 Enantiomer ( —— )

Catalog No. M11127 CAS No. 1268524-71-5

(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 55 Get Quote
5MG 105 Get Quote
10MG 177 Get Quote
25MG 357 Get Quote
50MG 557 Get Quote
100MG 791 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    (R)-(-)-JQ1 Enantiomer
  • Note
    Research use only, not for human use.
  • Brief Description
    (R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor.
  • Description
    (R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor, but (-)-JQ1 has no activity.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Bromodomain
  • Recptor
    Bromodomain
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1268524-71-5
  • Formula Weight
    456.99
  • Molecular Formula
    C23H25ClN4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
  • Chemical Name
    6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Filippakopoulos P, et al. Nature. 2010 Dec 23;468(7327):1067-73.
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